DNA structure and human diseases.
نویسندگان
چکیده
Recently, multiple lines of evidences have shown that non-B DNA structures within the human genes may lead to chromosomal translocations, deletions and amplifications in cancer and other human diseases. In this review, we summarize the current literature on non-B DNA structures, and discuss their role in genomic instability and diseases.
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عنوان ژورنال:
- Frontiers in bioscience : a journal and virtual library
دوره 12 شماره
صفحات -
تاریخ انتشار 2007